ϕ(2)GFP10, a High-Intensity Fluorophage, Enables Detection and Rapid Drug Susceptibility Testing of Mycobacterium tuberculosis Directly from Sputum Samples

The difficulty of diagnosing active tuberculosis (TB) and lack of rapid drug susceptibility testing (DST) at the point of care remain critical obstacles to TB control. This report describes a high-intensity mycobacterium-specific-fluorophage (ϕ(2)GFP10) that for the first time allows direct visualiz...

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Main Authors: Jain, Paras, Hartman, Travis E., Eisenberg, Nell, O'Donnell, Max R., Kriakov, Jordan, Govender, Karnishree, Makume, Mantha, Thaler, David S., Hatfull, Graham F., Sturm, A. Willem, Larsen, Michelle H., Moodley, Preshnie, Jacobs, William R.
Format: Artigo
Sprog:Inglês
Udgivet: American Society for Microbiology 2012
Fag:
Mycobacteriology and Aerobic Actinomycetes
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3318544/
https://ncbi.nlm.nih.gov/pubmed/22278833
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JCM.06192-11
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