Reduced aortic lesions and elevated high density lipoprotein levels in transgenic mice overexpressing mouse apolipoprotein A-IV.

Transgenic mouse lines carrying several copies of the mouse apo A-IV gene were produced. Lipoprotein composition and function, and aortic lesion development were examined. Apo A-IV levels in the plasma of transgenic mice were elevated threefold compared with nontransgenic littermates on a chow diet,...

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Publicado en:	J Clin Invest
Autores principales:	Cohen, R D, Castellani, L W, Qiao, J H, Van Lenten, B J, Lusis, A J, Reue, K
Formato:	Artigo
Lenguaje:	Inglês
Publicado:	American Society for Clinical Investigation 1997
Materias:	Research Article
Acceso en línea:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC508015/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/9109435/ https://ncbi.nlm.nih.govhttps://doi.org/10.1172/JCI119358
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