Mildly oxidized LDL induces an increased apolipoprotein J/paraoxonase ratio.

We have examined the effects of mildly oxidized LDL and atherosclerosis on the levels of two proteins associated with HDL; apolipoprotein J (apoJ), and paraoxonase (PON). On an atherogenic diet, PON activity decreased by 52%, and apoJ levels increased 2.8-fold in fatty streak susceptible mice, C57BL...

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Publicat a:J Clin Invest
Autors principals: Navab, M, Hama-Levy, S, Van Lenten, B J, Fonarow, G C, Cardinez, C J, Castellani, L W, Brennan, M L, Lusis, A J, Fogelman, A M, La Du, B N
Format: Artigo
Idioma:Inglês
Publicat: American Society for Clinical Investigation 1997
Matèries:
Research Article
Accés en línia:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC508026/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/9109446/
https://ncbi.nlm.nih.govhttps://doi.org/10.1172/JCI119369
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