A nucleotide substitution in the promoter of human angiotensinogen is associated with essential hypertension and affects basal transcription in vitro.

In earlier studies, we provided statistical evidence that individual differences in the angiotensinogen gene, the precursor of the vasoactive hormone angiotensin II, constitute inherited predispositions to essential hypertension in humans. We have now identified a common variant in the proximal prom...

詳細記述

保存先:
書誌詳細
主要な著者: Inoue, I, Nakajima, T, Williams, C S, Quackenbush, J, Puryear, R, Powers, M, Cheng, T, Ludwig, E H, Sharma, A M, Hata, A, Jeunemaitre, X, Lalouel, J M
フォーマット: Artigo
言語:Inglês
出版事項: 1997
主題:
Research Article
オンライン･アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC508000/
https://ncbi.nlm.nih.gov/pubmed/9120024
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