A nucleotide substitution in the promoter of human angiotensinogen is associated with essential hypertension and affects basal transcription in vitro.

In earlier studies, we provided statistical evidence that individual differences in the angiotensinogen gene, the precursor of the vasoactive hormone angiotensin II, constitute inherited predispositions to essential hypertension in humans. We have now identified a common variant in the proximal prom...

Ausführliche Beschreibung

Gespeichert in:
Bibliographische Detailangaben
Veröffentlicht in:J Clin Invest
Hauptverfasser: Inoue, I, Nakajima, T, Williams, C S, Quackenbush, J, Puryear, R, Powers, M, Cheng, T, Ludwig, E H, Sharma, A M, Hata, A, Jeunemaitre, X, Lalouel, J M
Format: Artigo
Sprache:Inglês
Veröffentlicht: American Society for Clinical Investigation 1997
Schlagworte:
Research Article
Online Zugang:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC508000/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/9120024/
https://ncbi.nlm.nih.govhttps://doi.org/10.1172/JCI119343
Tags: Tag hinzufügen
Keine Tags, Fügen Sie den ersten Tag hinzu!

Ähnliche Einträge