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Synthesis and evaluation of the structural elements in alkylated tetrahydroisoquinolines for binding to CNS receptors

Diseases of the CNS are often complex and involve multiple receptor systems and thus, the treatment options for these diseases must focus on targeting the multiple receptors implicated in the various disorders. Schizophrenia and depression are examples of such diseases and their pharmacotherapy thus...

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Détails bibliographiques
Publié dans:Bioorg Med Chem
Auteurs principaux: Ofori, Edward, Zhu, Xue Y., Etukala, Jagan R., Bricker, Barbara A., Ablordeppey, Seth Y.
Format: Artigo
Langue:Inglês
Publié: 2016
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC5079764/
https://ncbi.nlm.nih.gov/pubmed/27717652
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bmc.2016.09.019
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