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Enantioseparation of 5-chloro-2-(2-(3,4-dihydroisoquinoline-2(1H)-yl)ethyl)-2-methyl-2,3-dihydro-1H-inden-1-one (SYA 40247), a high affinity 5-HT(7) receptor ligand, by HPLC-PDA using amylose tris-(3, 5- dimethylphenylcarbamate) as a chiral stationary phase

In a previous structure activity relationship studies to identify new and selective 5-HT(7) receptor (5-HT(7)R) ligands, we have identified the chiral compound, 5-chloro-2-(2-(3,4-dihydroisoquinoline-2(1H)-yl)ethyl)-2-methyl-2,3-dihydro-1H-inden-1-one (SYA 40247), with high affinity binding to the 5...

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Detaylı Bibliyografya
Yayımlandı:Biomed Chromatogr
Asıl Yazarlar: Onyameh, Edem K., Bricker, Barbara A., Ofori, Edward, Ablordeppey, Seth Y.
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: 2019
Konular:
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC6685742/
https://ncbi.nlm.nih.gov/pubmed/31032988
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/bmc.4565
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