Development of CNS Multi-Receptor Ligands: Modification of Known D(2) Pharmacophores

Several known D(2) pharmacophores have been explored as templates for identifying ligands with multiple binding affinities at dopamine and serotonin receptors considered as clinically relevant receptors in the treatment of neuropsychiatric diseases. This approach has resulted in the identification o...

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Detalhes bibliográficos
Publicado no:Bioorg Med Chem
Main Authors: Etukala, Jagan R., Zhu, Xue Y., Eyunni, Suresh V. K., Onyameh, Edem K., Ofori, Edward, Bricker, Barbara, Huang, X. P., Kang, Hye J., Roth, Bryan L., Ablordeppey, Seth Y.
Formato: Artigo
Idioma:Inglês
Publicado em: 2016
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5209244/
https://ncbi.nlm.nih.gov/pubmed/27364609
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bmc.2016.06.011
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