Enhanced cleavage of type II collagen by collagenases in osteoarthritic articular cartilage.

We demonstrate the direct involvement of increased collagenase activity in the cleavage of type II collagen in osteoarthritic human femoral condylar cartilage by developing and using antibodies reactive to carboxy-terminal (COL2-3/4C(short)) and amino-terminal (COL2-1/4N1) neoepitopes generated by c...

Täydet tiedot

Bibliografiset tiedot

Julkaisussa:	J Clin Invest
Päätekijät:	Billinghurst, R C, Dahlberg, L, Ionescu, M, Reiner, A, Bourne, R, Rorabeck, C, Mitchell, P, Hambor, J, Diekmann, O, Tschesche, H, Chen, J, Van Wart, H, Poole, A R
Aineistotyyppi:	Artigo
Kieli:	Inglês
Julkaistu:	American Society for Clinical Investigation 1997
Aiheet:	Research Article
Linkit:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC507973/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/9119997/ https://ncbi.nlm.nih.govhttps://doi.org/10.1172/JCI119316
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