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Enhanced cleavage of type II collagen by collagenases in osteoarthritic articular cartilage.

We demonstrate the direct involvement of increased collagenase activity in the cleavage of type II collagen in osteoarthritic human femoral condylar cartilage by developing and using antibodies reactive to carboxy-terminal (COL2-3/4C(short)) and amino-terminal (COL2-1/4N1) neoepitopes generated by c...

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書誌詳細
出版年:J Clin Invest
主要な著者: Billinghurst, R C, Dahlberg, L, Ionescu, M, Reiner, A, Bourne, R, Rorabeck, C, Mitchell, P, Hambor, J, Diekmann, O, Tschesche, H, Chen, J, Van Wart, H, Poole, A R
フォーマット: Artigo
言語:Inglês
出版事項: American Society for Clinical Investigation 1997
主題:
オンライン・アクセス:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC507973/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/9119997/
https://ncbi.nlm.nih.govhttps://doi.org/10.1172/JCI119316
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