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Enhanced cleavage of type II collagen by collagenases in osteoarthritic articular cartilage.
We demonstrate the direct involvement of increased collagenase activity in the cleavage of type II collagen in osteoarthritic human femoral condylar cartilage by developing and using antibodies reactive to carboxy-terminal (COL2-3/4C(short)) and amino-terminal (COL2-1/4N1) neoepitopes generated by c...
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| Publicado no: | J Clin Invest |
|---|---|
| Main Authors: | , , , , , , , , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
American Society for Clinical Investigation
1997
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC507973/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/9119997/ https://ncbi.nlm.nih.govhttps://doi.org/10.1172/JCI119316 |
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