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GPRC6A Mediates Responses to Osteocalcin in β-Cells In Vitro and Pancreas In Vivo

A bone-pancreas endocrine loop has been identified recently that involves insulin secreted from β-cells in the pancreas stimulating insulin receptors in osteoblasts, leading to osteoblastic differentiation and increased secretion of osteocalcin (Ocn), a bone-derived hormone that regulates insulin se...

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Bibliographic Details
Published in:J Bone Miner Res
Main Authors: Pi, Min, Wu, Yunpeng, Quarles, L Darryl
Format: Artigo
Language:Inglês
Published: 2011
Subjects:
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC5079536/
https://ncbi.nlm.nih.gov/pubmed/21425331
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/jbmr.390
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