LFA-1 is sufficient in mediating neutrophil emigration in Mac-1-deficient mice.
To better define the specific function of Mac-1 (CD11b) versus LFA-1 (CD11a) and the other CD11 integrins in vivo, we have disrupted murine CD11b by targeted homologous recombination in embryonic stem cells and generated mice which are homozygous for a mutation in CD11b. A null mutation was confirme...
Zapisane w:
| Wydane w: | J Clin Invest |
|---|---|
| Główni autorzy: | , , , , , , , , |
| Format: | Artigo |
| Język: | Inglês |
| Wydane: |
American Society for Clinical Investigation
1997
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| Hasła przedmiotowe: | |
| Dostęp online: | https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC507950/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/9077544/ https://ncbi.nlm.nih.govhttps://doi.org/10.1172/JCI119293 |
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