LFA-1 is sufficient in mediating neutrophil emigration in Mac-1-deficient mice.

To better define the specific function of Mac-1 (CD11b) versus LFA-1 (CD11a) and the other CD11 integrins in vivo, we have disrupted murine CD11b by targeted homologous recombination in embryonic stem cells and generated mice which are homozygous for a mutation in CD11b. A null mutation was confirme...

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Detalhes bibliográficos
Main Authors: Lu, H, Smith, C W, Perrard, J, Bullard, D, Tang, L, Shappell, S B, Entman, M L, Beaudet, A L, Ballantyne, C M
Formato: Artigo
Idioma:Inglês
Publicado em: 1997
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC507950/
https://ncbi.nlm.nih.gov/pubmed/9077544
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