Proliferation of hepatic stellate cells is inhibited by phosphorylation of CREB on serine 133.

Proliferating, activated, hepatic stellate cells have a high level of collagen type I expression. Therefore, stellate cell proliferation is a critical step in hepatic fibrosis. Here we show that proliferation of activated primary rat stellate cells was blocked by elevation of cAMP with 8 Br-cAMP or...

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Εκδόθηκε σε:	J Clin Invest
Κύριοι συγγραφείς:	Houglum, K, Lee, K S, Chojkier, M
Μορφή:	Artigo
Γλώσσα:	Inglês
Έκδοση:	American Society for Clinical Investigation 1997
Θέματα:	Research Article
Διαθέσιμο Online:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC507948/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/9077542/ https://ncbi.nlm.nih.govhttps://doi.org/10.1172/JCI119291
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