Proliferation of hepatic stellate cells is inhibited by phosphorylation of CREB on serine 133.
Proliferating, activated, hepatic stellate cells have a high level of collagen type I expression. Therefore, stellate cell proliferation is a critical step in hepatic fibrosis. Here we show that proliferation of activated primary rat stellate cells was blocked by elevation of cAMP with 8 Br-cAMP or...
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| Udgivet i: | J Clin Invest |
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| Principais autores: | , , |
| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
American Society for Clinical Investigation
1997
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC507948/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/9077542/ https://ncbi.nlm.nih.govhttps://doi.org/10.1172/JCI119291 |
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