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Complete and sustained response of adult medulloblastoma to first-line sonic hedgehog inhibition with vismodegib

Medulloblastoma is an aggressive primitive neuroectodermal tumor of the cerebellum that is rare in adults. Medulloblastomas fall into 4 prognostically significant molecular subgroups that are best defined by experimental gene expression profiles: the WNT pathway, sonic hedgehog (SHH) pathway, and su...

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Опубликовано в: :Cancer Biol Ther
Главные авторы: Lou, Emil, Schomaker, Matthew, Wilson, Jon D., Ahrens, Mary, Dolan, Michelle, Nelson, Andrew C.
Формат: Artigo
Язык:Inglês
Опубликовано: Taylor & Francis 2016
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Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC5079386/
https://ncbi.nlm.nih.gov/pubmed/27682250
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1080/15384047.2016.1220453
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