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Differential response of SHH-expressing adult medulloblastomas to the sonic hedgehog inhibitor vismodegib: whole-genome analysis

Medulloblastoma is an aggressive primitive neuroectodermal tumor of the cerebellum that is more common in children than in adults. In the past decade, advances in understanding the molecular drivers of medulloblastoma have identified four molecular subgroups defined by experimental gene expression p...

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Bibliografische gegevens
Gepubliceerd in:Cancer Biol Ther
Hoofdauteurs: Lou, Emil, Nelson, Andrew C., Kool, Marcel
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: Taylor & Francis 2019
Onderwerpen:
Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6804804/
https://ncbi.nlm.nih.gov/pubmed/31423907
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1080/15384047.2019.1647057
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