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Population pharmacokinetics and pharmacodynamics of teicoplanin in neonates: making better use of C-reactive protein to deliver individualized therapy

OBJECTIVES: There is uncertainty about the optimal teicoplanin regimens for neonates. The study aim was to determine the population pharmacokinetics (PK) of teicoplanin in neonates, evaluate currently recommended regimens and explore the exposure–effect relationships. METHODS: An open-label PK study...

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Библиографические подробности
Опубликовано в: :J Antimicrob Chemother
Главные авторы: Ramos-Martín, V., Neely, M. N., McGowan, P., Siner, S., Padmore, K., Peak, M., Beresford, M. W., Turner, M. A., Paulus, S., Hope, W. W.
Формат: Artigo
Язык:Inglês
Опубликовано: Oxford University Press 2016
Предметы:
Original Research
Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC5079301/
https://ncbi.nlm.nih.gov/pubmed/27543654
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/jac/dkw295
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