Population pharmacokinetics and pharmacodynamics of teicoplanin in neonates: making better use of C-reactive protein to deliver individualized therapy

OBJECTIVES: There is uncertainty about the optimal teicoplanin regimens for neonates. The study aim was to determine the population pharmacokinetics (PK) of teicoplanin in neonates, evaluate currently recommended regimens and explore the exposure–effect relationships. METHODS: An open-label PK study...

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Detalhes bibliográficos
Publicado no:J Antimicrob Chemother
Main Authors: Ramos-Martín, V., Neely, M. N., McGowan, P., Siner, S., Padmore, K., Peak, M., Beresford, M. W., Turner, M. A., Paulus, S., Hope, W. W.
Formato: Artigo
Idioma:Inglês
Publicado em: Oxford University Press 2016
Assuntos:
Original Research
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5079301/
https://ncbi.nlm.nih.gov/pubmed/27543654
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/jac/dkw295
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