Direct visualization of the phenotype of hypoxic tumor cells at single cell resolution in vivo using a new hypoxia probe

Tumor hypoxia is linked to tumor progression, metastasis, and therapy resistance. However, the underlying mechanisms behind this linkage are not fully understood. Here we present a novel fluorescent mCherry hypoxia-responsive marker that can be used in real time imaging to specifically and sensitive...

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Bibliographic Details
Published in:Intravital
Main Authors: Wang, Yarong, Wang, Haoxuan, Li, Jiufeng, Entenberg, David, Xue, Alice, Wang, Weigang, Condeelis, John
Format: Artigo
Language:Inglês
Published: Taylor & Francis 2016
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Research Paper
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC5079291/
https://ncbi.nlm.nih.gov/pubmed/27790387
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1080/21659087.2016.1187803
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