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Nitroimidazoles as hypoxic cell radiosensitizers and hypoxia probes: misonidazole, myths and mistakes

Nitroimidazoles have been extensively explored as hypoxic cell radiosensitizers but have had limited clinical success, with efficacy restricted by toxicity. However, they have proven clinically useful as probes for tumour hypoxia. Both applications, and probably much of the dose-limiting toxicities,...

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Dades bibliogràfiques
Publicat a:Br J Radiol
Autor principal: Wardman, Peter
Format: Artigo
Idioma:Inglês
Publicat: The British Institute of Radiology. 2019
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC6435051/
https://ncbi.nlm.nih.gov/pubmed/29303355
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1259/bjr.20170915
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