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Nitroimidazoles as hypoxic cell radiosensitizers and hypoxia probes: misonidazole, myths and mistakes

Nitroimidazoles have been extensively explored as hypoxic cell radiosensitizers but have had limited clinical success, with efficacy restricted by toxicity. However, they have proven clinically useful as probes for tumour hypoxia. Both applications, and probably much of the dose-limiting toxicities,...

詳細記述

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書誌詳細
出版年:Br J Radiol
第一著者: Wardman, Peter
フォーマット: Artigo
言語:Inglês
出版事項: The British Institute of Radiology. 2019
主題:
オンライン・アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC6435051/
https://ncbi.nlm.nih.gov/pubmed/29303355
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1259/bjr.20170915
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