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Anticancer Drug Released from Near IR-activated Prodrug Overcomes Spatiotemporal Limits of Singlet Oxygen
Photodynamic therapy (PDT) is a cancer treatment modality where photosensitizer (PS) is activated by visible and near IR light to produce singlet oxygen ((1)O(2)). However, (1)O(2) has a short lifetime (< 40 ns) and cannot diffuse (< 20 nm) beyond the cell diameter (e.g., ~ 1,800 nm). Thus, (1...
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| Publicado no: | Bioorg Med Chem |
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| Main Authors: | , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2016
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5078988/ https://ncbi.nlm.nih.gov/pubmed/26928287 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bmc.2016.02.025 |
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