Folate-PEG Conjugates of a Far-Red Light-Activatable Paclitaxel Prodrug to Improve Selectivity toward Folate Receptor-Positive Cancer Cells

[Image: see text] We recently demonstrated the far-red light-activatable prodrug of paclitaxel (PTX), Pc-(L-PTX)(2). Upon illumination with a 690 nm laser, Pc-(L-PTX)(2) showed combinational cell killing from rapid photodynamic therapy damage by singlet oxygen, followed by sustained chemotherapy eff...

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Bibliografiska uppgifter
I publikationen:ACS Omega
Huvudupphovsmän: Thapa, Pritam, Li, Mengjie, Karki, Radha, Bio, Moses, Rajaputra, Pallavi, Nkepang, Gregory, Woo, Sukyung, You, Youngjae
Materialtyp: Artigo
Språk:Inglês
Publicerad: American Chemical Society 2017
Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC5664141/
https://ncbi.nlm.nih.gov/pubmed/29104951
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/acsomega.7b01105
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