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DNA Damage: From Chronic Inflammation to Age-Related Deterioration

To lessen the “wear and tear” of existence, cells have evolved mechanisms that continuously sense DNA lesions, repair DNA damage and restore the compromised genome back to its native form. Besides genome maintenance pathways, multicellular organisms may also employ adaptive and innate immune mechani...

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Detalhes bibliográficos
Publicado no:Front Genet
Main Authors: Ioannidou, Anna, Goulielmaki, Evi, Garinis, George A.
Formato: Artigo
Idioma:Inglês
Publicado em: Frontiers Media S.A. 2016
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5078321/
https://ncbi.nlm.nih.gov/pubmed/27826317
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fgene.2016.00187
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