In vivo screening and discovery of novel candidate thalidomide analogs in the zebrafish embryo and chicken embryo model systems

Thalidomide, a drug known for its teratogenic side-effects, is used successfully to treat a variety of clinical conditions including leprosy and multiple myeloma. Intense efforts are underway to synthesize and identify safer, clinically relevant analogs. Here, we conduct a preliminary in vivo screen...

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Veröffentlicht in:Oncotarget
Hauptverfasser: Beedie, Shaunna L., Rore, Holly M., Barnett, Shelby, Chau, Cindy H., Luo, Weiming, Greig, Nigel H., Figg, William D., Vargesson, Neil
Format: Artigo
Sprache:Inglês
Veröffentlicht: Impact Journals LLC 2016
Schlagworte:
Research Paper
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5078090/
https://ncbi.nlm.nih.gov/pubmed/27120781
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.18632/oncotarget.8909
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