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Shared mechanism of teratogenicity of anti-angiogenic drugs identified in the chicken embryo model

Angiogenesis, the formation of new blood vessels, is essential for tumor growth, stabilization and progression. Angiogenesis inhibitors are now widely used in the clinic; however, there are relatively few published studies on the mechanism of their presumed teratogenic effects. To address this issue...

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Detalhes bibliográficos
Publicado no:Sci Rep
Main Authors: Beedie, Shaunna L., Mahony, Chris, Walker, Heather M., Chau, Cindy H., Figg, William D., Vargesson, Neil
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group 2016
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4957076/
https://ncbi.nlm.nih.gov/pubmed/27443489
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/srep30038
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