Epigenetic reader BRD4 inhibition as a therapeutic strategy to suppress E2F2-cell cycle regulation circuit in liver cancer

Deregulation of the epigenome component affects multiple pathways in the cancer phenotype since the epigenome acts at the pinnacle of the hierarchy of gene expression. Pioneering work over the past decades has highlighted that targeting enzymes or proteins involved in the epigenetic regulation is a...

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Udgivet i:Oncotarget
Main Authors: Hong, Seong Hwi, Eun, Jung Woo, Choi, Sung Kyung, Shen, Qingyu, Choi, Wahn Soo, Han, Jeung-Whan, Nam, Suk Woo, You, Jueng Soo
Format: Artigo
Sprog:Inglês
Udgivet: Impact Journals LLC 2016
Fag:
Research Paper
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5078039/
https://ncbi.nlm.nih.gov/pubmed/27081696
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.18632/oncotarget.8701
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