A COL11A1-correlated pan-cancer gene signature of activated fibroblasts for the prioritization of therapeutic targets

Although cancer-associated fibroblasts (CAFs) are viewed as a promising therapeutic target, the design of rational therapy has been hampered by two key obstacles. First, attempts to ablate CAFs have resulted in significant toxicity because currently used biomarkers cannot effectively distinguish act...

Descripció completa

Guardat en:
Dades bibliogràfiques
Publicat a:Cancer Lett
Autors principals: Jia, Dongyu, Liu, Zhenqiu, Deng, Nan, Tan, Tuan Zea, Huang, Ruby Yun-Ju, Taylor-Harding, Barbie, Cheon, Dong-Joo, Lawrenson, Kate, Wiedemeyer, Wolf R., Walts, Ann E., Karlan, Beth Y., Orsulic, Sandra
Format: Artigo
Idioma:Inglês
Publicat: 2016
Matèries:
Article
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC5077659/
https://ncbi.nlm.nih.gov/pubmed/27609069
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.canlet.2016.09.001
Etiquetes: Afegir etiqueta
Sense etiquetes, Sigues el primer a etiquetar aquest registre!

Ítems similars