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A Combination of Diffusion and Active Translocation Localizes Myosin 10 to the Filopodial Tip

Myosin 10 is an actin-based molecular motor that localizes to the tips of filopodia in mammalian cells. To understand how it is targeted to this distinct region of the cell, we have used total internal reflection fluorescence microscopy to study the movement of individual full-length and truncated G...

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Bibliografiske detaljer
Udgivet i:J Biol Chem
Main Authors: Baboolal, Thomas G., Mashanov, Gregory I., Nenasheva, Tatiana A., Peckham, Michelle, Molloy, Justin E.
Format: Artigo
Sprog:Inglês
Udgivet: American Society for Biochemistry and Molecular Biology 2016
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5077179/
https://ncbi.nlm.nih.gov/pubmed/27566544
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M116.730689
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