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Direct Observation of Individual KCNQ1 Potassium Channels Reveals Their Distinctive Diffusive Behavior

We have directly observed the trafficking and fusion of ion channel containing vesicles and monitored the release of individual ion channels at the plasma membrane of live mammalian cells using total internal reflection fluorescence microscopy. Proteins were fused in-frame with green or red fluoresc...

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Detalhes bibliográficos
Main Authors: Mashanov, Gregory I., Nobles, Muriel, Harmer, Stephen C., Molloy, Justin E., Tinker, Andrew
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Biochemistry and Molecular Biology 2010
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2823507/
https://ncbi.nlm.nih.gov/pubmed/19940153
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M109.039974
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