The Tax-Inducible Actin-Bundling Protein Fascin Is Crucial for Release and Cell-to-Cell Transmission of Human T-Cell Leukemia Virus Type 1 (HTLV-1)

The delta-retrovirus Human T-cell leukemia virus type 1 (HTLV-1) preferentially infects CD4(+) T-cells via cell-to-cell transmission. Viruses are transmitted by polarized budding and by transfer of viral biofilms at the virological synapse (VS). Formation of the VS requires the viral Tax protein and...

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Detalles Bibliográficos
Publicado en:PLoS Pathog
Main Authors: Gross, Christine, Wiesmann, Veit, Millen, Sebastian, Kalmer, Martina, Wittenberg, Thomas, Gettemans, Jan, Thoma-Kress, Andrea K.
Formato: Artigo
Idioma:Inglês
Publicado: Public Library of Science 2016
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Research Article
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC5077169/
https://ncbi.nlm.nih.gov/pubmed/27776189
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.ppat.1005916
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