The Skp1 Homologs SKR-1/2 Are Required for the Caenorhabditis elegans SKN-1 Antioxidant/Detoxification Response Independently of p38 MAPK

SKN-1/Nrf are the primary antioxidant/detoxification response transcription factors in animals and they promote health and longevity in many contexts. SKN-1/Nrf are activated by a remarkably broad-range of natural and synthetic compounds and physiological conditions. Defining the signaling mechanism...

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Bibliografiska uppgifter
I publikationen:PLoS Genet
Huvudupphovsmän: Wu, Cheng-Wei, Deonarine, Andrew, Przybysz, Aaron, Strange, Kevin, Choe, Keith P.
Materialtyp: Artigo
Språk:Inglês
Publicerad: Public Library of Science 2016
Ämnen:
Research Article
Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC5077136/
https://ncbi.nlm.nih.gov/pubmed/27776126
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pgen.1006361
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