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The WD40 Repeat Protein WDR-23 Functions with the CUL4/DDB1 Ubiquitin Ligase To Regulate Nuclear Abundance and Activity of SKN-1 in Caenorhabditis elegans

The transcription factor SKN-1 protects Caenorhabditis elegans from stress and promotes longevity. SKN-1 is regulated by diverse signals that control metabolism, development, and stress responses, but the mechanisms of regulation and signal integration are unknown. We screened the C. elegans genome...

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Detalhes bibliográficos
Main Authors: Choe, Keith P., Przybysz, Aaron J., Strange, Kevin
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology (ASM) 2009
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2682033/
https://ncbi.nlm.nih.gov/pubmed/19273594
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/MCB.01811-08
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