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The WD40 Repeat Protein WDR-23 Functions with the CUL4/DDB1 Ubiquitin Ligase To Regulate Nuclear Abundance and Activity of SKN-1 in Caenorhabditis elegans
The transcription factor SKN-1 protects Caenorhabditis elegans from stress and promotes longevity. SKN-1 is regulated by diverse signals that control metabolism, development, and stress responses, but the mechanisms of regulation and signal integration are unknown. We screened the C. elegans genome...
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Main Authors: | , , |
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Formato: | Artigo |
Idioma: | Inglês |
Publicado em: |
American Society for Microbiology (ASM)
2009
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Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2682033/ https://ncbi.nlm.nih.gov/pubmed/19273594 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/MCB.01811-08 |
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