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Increased age reduces DAF-16 and SKN-1 signaling and the hormetic response of Caenorhabditis elegans to the xenobiotic juglone

Cells adapt to stressors by activating mechanisms that repair damage and protect them from further injury. Stress-induced damage accumulates with age and contributes to age associated diseases. Increased age attenuates the ability to mount a stress response, but little is known about the mechanisms...

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Detalhes bibliográficos
Main Authors: Przybysz, Aaron J., Choe, Keith P., Roberts, L. Jackson, Strange, Kevin
Formato: Artigo
Idioma:Inglês
Publicado em: 2009
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2680786/
https://ncbi.nlm.nih.gov/pubmed/19428455
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.mad.2009.02.004
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