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Magnetic resonance evidence of hypoxia in a homozygous alpha-knockout of a transgenic mouse model for sickle cell disease.

All transgenic mouse models for sickle cell disease express residual levels of mouse globins which complicate the interpretation of experimental results. We now report on a mouse expressing high levels of human betaS and 100% human alpha-globin. These mice were created by breeding the alpha-knockout...

Täydet tiedot

Tallennettuna:
Bibliografiset tiedot
Päätekijät: Fabry, M E, Kennan, R P, Paszty, C, Costantini, F, Rubin, E M, Gore, J C, Nagel, R L
Aineistotyyppi: Artigo
Kieli:Inglês
Julkaistu: 1996
Aiheet:
Linkit:https://ncbi.nlm.nih.gov/pmc/articles/PMC507701/
https://ncbi.nlm.nih.gov/pubmed/8958206
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