The Steroid Hormone 20-Hydroxyecdysone Promotes the Cytoplasmic Localization of Yorkie to Suppress Cell Proliferation and Induce Apoptosis

The transcriptional co-activator Yki (Yorkie), a member of the Hippo pathway, regulates cell proliferation or apoptosis, depending on its nuclear or cytoplasmic location. However, the upstream factors regulating the subcellular localization of Yki are unclear. We found that the steroid hormone 20-hy...

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Bibliographic Details
Published in:J Biol Chem
Main Authors: Wang, Di, Li, Xiang-Ru, Dong, Du-Juan, Huang, Hua, Wang, Jin-Xing, Zhao, Xiao-Fan
Format: Artigo
Language:Inglês
Published: American Society for Biochemistry and Molecular Biology 2016
Subjects:
Cell Biology
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC5076844/
https://ncbi.nlm.nih.gov/pubmed/27551043
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M116.719856
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