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The Steroid Hormone 20-Hydroxyecdysone Promotes the Cytoplasmic Localization of Yorkie to Suppress Cell Proliferation and Induce Apoptosis

The transcriptional co-activator Yki (Yorkie), a member of the Hippo pathway, regulates cell proliferation or apoptosis, depending on its nuclear or cytoplasmic location. However, the upstream factors regulating the subcellular localization of Yki are unclear. We found that the steroid hormone 20-hy...

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Detalhes bibliográficos
Publicado no:J Biol Chem
Main Authors: Wang, Di, Li, Xiang-Ru, Dong, Du-Juan, Huang, Hua, Wang, Jin-Xing, Zhao, Xiao-Fan
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Biochemistry and Molecular Biology 2016
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5076844/
https://ncbi.nlm.nih.gov/pubmed/27551043
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M116.719856
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