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The steroid hormone 20-hydroxyecdysone counteracts insulin signaling via insulin receptor dephosphorylation

The insulin receptor (INSR) binds insulin to promote body growth and maintain normal blood glucose levels. While it is known that steroid hormones such as estrogen and 20-hydroxyecdysone counteract insulin function, the molecular mechanisms responsible for this attenuation remain unclear. In the pre...

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Bibliografische gegevens
Gepubliceerd in:J Biol Chem
Hoofdauteurs: Li, Yan-Li, Yao, You-Xiang, Zhao, Yu-Meng, Di, Yu-Qin, Zhao, Xiao-Fan
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: American Society for Biochemistry and Molecular Biology 2021
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Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7949120/
https://ncbi.nlm.nih.gov/pubmed/33484713
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jbc.2021.100318
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