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The steroid hormone 20-hydroxyecdysone counteracts insulin signaling via insulin receptor dephosphorylation

The insulin receptor (INSR) binds insulin to promote body growth and maintain normal blood glucose levels. While it is known that steroid hormones such as estrogen and 20-hydroxyecdysone counteract insulin function, the molecular mechanisms responsible for this attenuation remain unclear. In the pre...

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Dades bibliogràfiques
Publicat a:J Biol Chem
Autors principals: Li, Yan-Li, Yao, You-Xiang, Zhao, Yu-Meng, Di, Yu-Qin, Zhao, Xiao-Fan
Format: Artigo
Idioma:Inglês
Publicat: American Society for Biochemistry and Molecular Biology 2021
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC7949120/
https://ncbi.nlm.nih.gov/pubmed/33484713
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jbc.2021.100318
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