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The steroid hormone 20-hydroxyecdysone counteracts insulin signaling via insulin receptor dephosphorylation

The insulin receptor (INSR) binds insulin to promote body growth and maintain normal blood glucose levels. While it is known that steroid hormones such as estrogen and 20-hydroxyecdysone counteract insulin function, the molecular mechanisms responsible for this attenuation remain unclear. In the pre...

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Detaylı Bibliyografya
Yayımlandı:J Biol Chem
Asıl Yazarlar: Li, Yan-Li, Yao, You-Xiang, Zhao, Yu-Meng, Di, Yu-Qin, Zhao, Xiao-Fan
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: American Society for Biochemistry and Molecular Biology 2021
Konular:
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC7949120/
https://ncbi.nlm.nih.gov/pubmed/33484713
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jbc.2021.100318
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