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Nuclear Export of FoxO1 Is Associated with ERK Signaling in β-Cells Lacking Insulin Receptors

The insulin/insulin-like growth factor (IGF) signaling pathway plays a critical role in the regulation of islet cell biology. However, the signaling pathway(s) utilized by insulin to directly modulate β-cells is unclear. To interrogate whether insulin exerts endocrine effects in regulating proteins...

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Détails bibliographiques
Publié dans:J Biol Chem
Auteurs principaux: Mezza, Teresa, Shirakawa, Jun, Martinez, Rachael, Hu, Jiang, Giaccari, Andrea, Kulkarni, Rohit N.
Format: Artigo
Langue:Inglês
Publié: American Society for Biochemistry and Molecular Biology 2016
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC5076820/
https://ncbi.nlm.nih.gov/pubmed/27535223
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M116.735738
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