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Nuclear Export-independent Inhibition of Foxa2 by Insulin
The Forkhead box A2 transcription factor (Foxa2/HNF-3β) has been shown to be a key regulator of genes involved in the maintenance of glucose and lipid homeostasis in the liver. It is constitutively inactivated in several hyperinsulinemic/obese mouse models, thereby enhancing their metabolic phenotyp...
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| Main Authors: | , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
American Society for Biochemistry and Molecular Biology
2009
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2757185/ https://ncbi.nlm.nih.gov/pubmed/19589781 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M109.042135 |
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