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The Assembly Factor SDHAF2 Is Dispensable for Flavination of the Catalytic Subunit of Mitochondrial Complex II in Breast Cancer Cells

Mitochondrial complex II or succinate dehydrogenase (SDH) is at the crossroads of oxidative phosphorylation and the tricarboxylic acid cycle. It has been shown that Sdh5 (SDHAF2/SDH5 in mammals) is required for flavination of the subunit Sdh1 (SDHA in human cells) in yeast. Here we demonstrate that...

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Pubblicato in:J Biol Chem
Autori principali: Bezawork-Geleta, Ayenachew, Dong, Lanfeng, Rohlena, Jakub, Neuzil, Jiri
Natura: Artigo
Lingua:Inglês
Pubblicazione: American Society for Biochemistry and Molecular Biology 2016
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC5076811/
https://ncbi.nlm.nih.gov/pubmed/27587393
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.C116.755017
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