Mitochondrially targeted vitamin E succinate efficiently kills breast tumour-initiating cells in a complex II-dependent manner

BACKGROUND: Accumulating evidence suggests that breast cancer involves tumour-initiating cells (TICs), which play a role in initiation, metastasis, therapeutic resistance and relapse of the disease. Emerging drugs that target TICs are becoming a focus of contemporary research. Mitocans, a group of c...

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Detalhes bibliográficos
Publicado no:BMC Cancer
Main Authors: Yan, Bing, Stantic, Marina, Zobalova, Renata, Bezawork-Geleta, Ayenachew, Stapelberg, Michael, Stursa, Jan, Prokopova, Katerina, Dong, Lanfeng, Neuzil, Jiri
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2015
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4494715/
https://ncbi.nlm.nih.gov/pubmed/25967547
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12885-015-1394-7
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