In the absence of the low density lipoprotein receptor, human apolipoprotein C1 overexpression in transgenic mice inhibits the hepatic uptake of very low density lipoproteins via a receptor-associated protein-sensitive pathway.

Παρόμοια τεκμήρια

• Reversal of hyperlipidaemia in apolipoprotein C1 transgenic mice by adenovirus-mediated gene delivery of the low-density-lipoprotein receptor, but not by the very-low-density-lipoprotein receptor.
  ανά: Jong, M C, κ.ά.
  Έκδοση: (1999)
• Very-low-density lipoprotein binding to the apolipoprotein E receptor 2 is enhanced by lipoprotein lipase, and does not require apolipoprotein E.
  ανά: Tacken, P J, κ.ά.
  Έκδοση: (2000)
• Nascent very-low-density lipoprotein triacylglycerol hydrolysis by lipoprotein lipase is inhibited by apolipoprotein E in a dose-dependent manner.
  ανά: Jong, M C, κ.ά.
  Έκδοση: (1997)
• Reduced very-low-density lipoprotein fractional catabolic rate in apolipoprotein C1-deficient mice.
  ανά: Jong, M C, κ.ά.
  Έκδοση: (1997)
• Modulation of very low density lipoprotein production and clearance contributes to age- and gender- dependent hyperlipoproteinemia in apolipoprotein E3-Leiden transgenic mice.
  ανά: van Vlijmen, B J, κ.ά.
  Έκδοση: (1996)