A carregar...
Kinetic and Structural Impact of Metal Ions and Genetic Variations on Human DNA Polymerase ι
DNA polymerase (pol) ι is a Y-family polymerase involved in translesion synthesis, exhibiting higher catalytic activity with Mn(2+) than Mg(2+). The human germline R96G variant impairs both Mn(2+)-dependent and Mg(2+)-dependent activities of pol ι, whereas the Δ1–25 variant selectively enhances its...
Na minha lista:
| Publicado no: | J Biol Chem |
|---|---|
| Main Authors: | , , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
American Society for Biochemistry and Molecular Biology
2016
|
| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5076516/ https://ncbi.nlm.nih.gov/pubmed/27555320 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M116.748285 |
| Tags: |
Adicionar Tag
Sem tags, seja o primeiro a adicionar uma tag!
|