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Allostery Wiring Map for Kinesin Energy Transduction and Its Evolution

How signals between the kinesin active and cytoskeletal binding sites are transmitted is an open question and an allosteric question. By extracting correlated evolutionary changes within 700+ sequences, we built a model of residues that are energetically coupled and that define molecular routes for...

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Detalhes bibliográficos
Publicado no:J Biol Chem
Main Authors: Richard, Jessica, Kim, Elizabeth D., Nguyen, Hoang, Kim, Catherine D., Kim, Sunyoung
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Biochemistry and Molecular Biology 2016
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5076506/
https://ncbi.nlm.nih.gov/pubmed/27507814
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M116.733675
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