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The Phylogeny and Active Site Design of Eukaryotic Copper-only Superoxide Dismutases

In eukaryotes the bimetallic Cu/Zn superoxide dismutase (SOD) enzymes play important roles in the biology of reactive oxygen species by disproportionating superoxide anion. Recently, we reported that the fungal pathogen Candida albicans expresses a novel copper-only SOD, known as SOD5, that lacks th...

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Pubblicato in:J Biol Chem
Autori principali: Peterson, Ryan L., Galaleldeen, Ahmad, Villarreal, Johanna, Taylor, Alexander B., Cabelli, Diane E., Hart, P. John, Culotta, Valeria C.
Natura: Artigo
Lingua:Inglês
Pubblicazione: American Society for Biochemistry and Molecular Biology 2016
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC5076504/
https://ncbi.nlm.nih.gov/pubmed/27535222
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M116.748251
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