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Degradation of nuclear oncoproteins by the ubiquitin system in vitro.

Nuclear oncoproteins are among the most rapidly degraded intracellular proteins. Previous work has implicated the ubiquitin-mediated proteolytic system in the turnover of short-lived intracellular proteins. In the present study, we have evaluated the potential role of the ubiquitin system in the deg...

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Veröffentlicht in:Proc Natl Acad Sci U S A
Hauptverfasser: Ciechanover, A, DiGiuseppe, J A, Bercovich, B, Orian, A, Richter, J D, Schwartz, A L, Brodeur, G M
Format: Artigo
Sprache:Inglês
Veröffentlicht: National Academy of Sciences 1991
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Online-Zugang:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC50765/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/1846034/
https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.88.1.139
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