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RNF2 promotes chondrosarcoma progression by regulating ubiquitination and degradation of CBX7

Abstract Objective Chondrosarcoma (CHS) is resistant to conventional chemotherapy and radiotherapy and currently lacks effective treatment options when in advanced stages. Accordingly, this research investigated the mechanism of RNF2/CBX7 in CHS to drive the development of molecularly targeted drugs...

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Autors principals: Yue Wu, Zheng Huang, Ping Luo, Zhong Xiang, Meng Zhang, Zhiwu Chen, Yalu Zhou, Jiameng Li
Format: Artigo
Idioma:Inglês
Publicat: BMC 2024-10-01
Col·lecció:Cancer & Metabolism
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Accés en línia:https://doi.org/10.1186/s40170-024-00359-x
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