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RNF149 negatively regulates LPS/TLR4 signal transduction by ubiquitination-mediated CD63 degradation

This study aims to investigate the role of RNF149 and tetraspanin CD63 in lipopolysaccharide/Toll-like receptor 4 (LPS/TLR4) signal transduction. TNF-α was assessed using enzyme-linked immunosorbent assay. The distribution of TLR4 was examined through flow cytometry after CD63 knockdown. Real-time p...

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I tiakina i:
Ngā taipitopito rārangi puna kōrero
Ngā kaituhi matua: Xiu-An Yang, Yingying Wang, Mingyu Gong, Zicheng Zhao, Fengchun Lv, Xiaoyu Zhang, Yan Li
Hōputu: Artigo
Reo:Inglês
I whakaputaina: Elsevier 2024-07-01
Rangatū:Heliyon
Ngā marau:
Urunga tuihono:http://www.sciencedirect.com/science/article/pii/S2405844024103817
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