Demonstration of an osteoblast defect in two cases of human malignant osteopetrosis. Correction of the phenotype after bone marrow transplant.

Osteopetrosis is an inherited disorder characterized by bone sclerosis due to reduced bone resorption. Here we report that human osteopetrotic osteoblast-like (Ob) cells express a defective phenotype in primary cultures in vitro, and that bone marrow transplant (BMT) corrects osteoblast function. DN...

詳細記述

書誌詳細

出版年:	J Clin Invest
主要な著者:	Lajeunesse, D, Busque, L, Ménard, P, Brunette, M G, Bonny, Y
フォーマット:	Artigo
言語:	Inglês
出版事項:	American Society for Clinical Investigation 1996
主題:	Research Article
オンライン･アクセス:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC507623/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/8878435/ https://ncbi.nlm.nih.govhttps://doi.org/10.1172/JCI118984
タグ:	タグ追加 タグなし, このレコードへの初めてのタグを付けませんか!